Midodrine

Generic name: midodrine [ MY-doe-drin ]
Brand names: ProAmatine, Orvaten
Dosage form: oral tablet (10 mg; 2.5 mg; 5 mg)
Drug class:Miscellaneous cardiovascular agents

Medically reviewed by Drugs.com on Feb 7, 2022. Written by Cerner Multum.

What is midodrine?

Midodrine works by constricting (narrowing) the blood vessels and increasing blood pressure.

Midodrine is used to treat low blood pressure (hypotension) that causes severe dizziness or a light-headed feeling, like you might pass out. midodrine is for use only when low blood pressure affects daily life. Midodrine may not improve your ability to perform daily activities.

Midodrine may also be used for purposes not listed in this medication guide.

Warnings

You should not use midodrine if you have severe heart disease, overactive thyroid, an adrenal gland tumor, kidney disease, if you are unable to urinate, or if your blood pressure is high even while lying down.

Midodrine can increase blood pressure even when you are at rest. This medicine should be used only if you have severely low blood pressure that affects your daily life. Midodrine may not improve your ability to perform daily activities.

Before taking this medicine

You should not use midodrine if you are allergic to it, or if you have:

• severe heart disease;

• kidney disease, or if you are unable to urinate;

• pheochromocytoma (tumor of the adrenal gland);

• overactive thyroid; or

• high blood pressure even while lying down.

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