MigraTen

Generic name:acetaminophen, caffeine, and isometheptene [ a-SEET-a-MIN-o-fen, KAF-een, EYE-soe-meth-EP-teen ]
Brand names: MigraTen, Prodrin
Drug class:Analgesic combinations

Medically reviewed by Drugs.com. Last updated on Sep 9, 2021.

What is MigraTen?

MigraTen contains a combination of acetaminophen, caffeine, and isometheptene. Acetaminophen is a pain reliever and a fever reducer. Caffeine is a stimulant that causes narrowing of blood vessels (vasoconstriction). Isometheptene also causes narrowing of blood vessels. This is important in the treatment of headaches.

MigraTen is used to treat migraine headaches or severe tension headaches.

MigraTen may also be used for purposes not listed in this medication guide.

Warnings

Tell your doctor if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take medicine that contains acetaminophen.

Do not take more MigraTen than is recommended. An overdose of acetaminophen can damage your liver or cause death.

Do not use MigraTen if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

Before taking this medicine

Tell your doctor if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take medicine that contains acetaminophen. Do not use MigraTen if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

You should not take MigraTen if you are allergic to acetaminophen (Tylenol), caffeine, or isometheptene, or if you have:

• glaucoma;

• severe kidney disease;

• severe liver disease (especially cirrhosis);

• severe or uncontrolled high blood pressure; or

• heart disease.

To make sure you can safely take MigraTen, tell your doctor if you have any of these other conditions:

• kidney or liver disease;

• a history of alcoholism;

• high blood pressure;

• blood circulation problems; or

• if you have recently had a heart attack.

FDA pregnancy category C. It is not known whether MigraTe...