Movantik

Generic name:naloxegol [ nal-OX-ee-gol ]
Drug class:Peripheral opioid receptor antagonists

Medically reviewed by Sanjai Sinha, MD. Last updated on Oct 1, 2021.

What is Movantik?

Movantik blocks certain effects of opioid medication. An opioid is sometimes called a narcotic.

Movantik reduces constipation caused by opioid pain medicine used to treat severe chronic pain. Naloxegol works by treating constipation without reducing the pain-relieving effects of the opioid.

Movantik is used in people who have been taking opioid pain medicine for at least 4 weeks, to treat chronic pain that is not caused by cancer.

Warnings

You should not use Movantik if you have a blockage in your stomach or intestines.

Tell your doctor if you have symptoms of opioid withdrawal, such as anxiety, feeling irritable, sweating, chills, yawning, stomach pain, and diarrhea.

Stop using naloxegol and call your doctor at once if you have severe stomach pain and/or diarrhea (which can lead to serious medical problems).

Many drugs can interact with naloxegol, and some drugs should not be used together. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Movantik.

Before taking this medicine

You should not use Movantik if you are allergic to naloxegol, or if you have:

• a blockage in your stomach or intestines.

Some medicines can cause unwanted or dangerous effects when used with naloxegol. Your doctor may need to change your treatment plan if you also use:

• certain antibiotics;

• imatinib;

• isoniazid;

• nefazodone;

• ...