Moxetumomab pasudotox
Generic name: moxetumomab pasudotox [ MOX-e-TOOM-oh-mab-pa-SOO-doe-tox ]
Brand name: Lumoxiti
Dosage form: intravenous powder for injection (1 mg)
Drug class:Miscellaneous antineoplastics
What is moxetumomab pasudotox?
Moxetumomab pasudotox is used to treat adults with hairy cell leukemia.
Moxetumomab pasudotox is given after at least two other cancer treatments did not work or have stopped working.
Moxetumomab pasudotox may also be used for purposes not listed in this medication guide.
Warnings
Moxetumomab pasudotox can damage your kidneys, especially if you already have kidney disease or if you are 65 years of age or older. Get emergency medical help if you have: unusual bruising or bleeding, fever, confusion, tiredness or irritability, stomach pain, vomiting, dark urine, fast heartbeats, and little or no urination.
Before taking this medicine
Tell your doctor if you have ever had:
kidney disease; or
a condition that affects your blood and blood vessels (such as hemolytic uremic syndrome or severe thrombotic microangiopathy).
You may need to have a negative pregnancy test before starting this treatment.
Do not use moxetumomab pasudotox if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using moxetumomab pasudotox and for at least 30 days after your last dose. Tell your doctor right away if you become pregnant.
You should not breastfeed while using moxetumomab pasudotox.
How is moxetumomab pasudotox given?
Moxetumomab pasudotox is given as an infusion into a vein. A healthcare provider will give you this injection.
This medicine must be given slowly, and the infusion can take about 30 minutes to complete.
You may be given other medications to help prevent serious side effects or an infusion reaction. Keep using these medicines for as long as your doctor has prescribed.
Moxetumomab pasudotox is given in a 28-day treatment cycle. You may need to use the medicine only during the first week of each cycle. You may receive up to 6 treatment cycles. Your doctor will determine how long to treat you with this medicine.
During the first 8 days of each treatment cycle, drink up to 12 full 8-ounce glasses of water, milk, or juice every 24 hours.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your moxetumomab pasudotox injection.
What happens if I overdose?
Since moxetumomab pasudotox is given by a healthcare ...
