Moxetumomab pasudotox-tdfk (Intravenous)
Medically reviewed by Drugs.com. Last updated on Dec 31, 2021.
Warning: Capillary Leak Syndrome And Hemolytic Uremic SyndromeCapillary Leak Syndrome (CLS), including life-threatening cases, occurred in patients receiving moxetumomab pasudotox-tdfk. Monitor weight and blood pressure; check labs, including albumin, if CLS is suspected. Delay dosing or discontinue moxetumomab pasudotox-tdfk as recommended.Hemolytic Uremic Syndrome (HUS), including life-threatening cases, occurred in patients receiving moxetumomab pasudotox-tdfk. Monitor hemoglobin, platelet count, serum creatinine, and ensure adequate hydration. Discontinue moxetumomab pasudotox-tdfk in patients with HUS .
Commonly used brand name(s)
In the U.S.
- Lumoxiti
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Antineoplastic Agent
Pharmacologic Class: Moxetumomab Pasudotox
Uses for moxetumomab pasudotox-tdfk
Moxetumomab pasudotox-tdfk injection is used to treat hairy cell leukemia that has worsened or cannot be completely removed in patients who have had at least two previous treatments that did not work well.
Moxetumomab pasudotox-tdfk is to be given only by or under the direct supervision of your doctor.
Before using moxetumomab pasudotox-tdfk
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For moxetumomab pasudotox-tdfk, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to moxetumomab pasudotox-tdfk or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of moxetumomab pasudotox-tdfk injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of moxetumomab pasudotox-tdfk injection in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution for patients receiving moxetumomab pasudotox-tdfk.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since i..
