Class: Quinolones
VA Class: AM900
Chemical Name: (4aS-cis)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(octahydro-6H-pyrrolol[3,4-b]pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid monohydrochloride
Molecular Formula: C21H24FN3O4
CAS Number: 186826-86-8
Brands: Avelox
Warning
- Serious Adverse Reactions
Fluoroquinolones, including moxifloxacin, have been associated with disabling and potentially irreversible serious adverse reactions (e.g., tendinitis and tendon rupture, peripheral neuropathy, CNS effects) that have occurred together. Discontinue immediately and avoid use of fluoroquinolones, including moxifloxacin, in patients who have experienced any of these serious adverse reactions. (See Warnings under Cautions.)
Fluoroquinolones, including moxifloxacin, may exacerbate muscle weakness in patients with myasthenia gravis. Avoid in patients with known history of myasthenia gravis.
Because of risk of serious adverse reactions, use moxifloxacin for treatment of acute bacterial sinusitis or acute bacterial exacerbations of chronic bronchitis only when no other treatment options available.
Introduction
Antibacterial; fluoroquinolone.
Uses for Moxifloxacin (Systemic)
Respiratory Tract Infections
Treatment of acute bacterial sinusitis caused by susceptible Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis.
Treatment of acute bacterial exacerbations of chronic bronchitis caused by susceptible S. pneumoniae, H. influenzae, H. parainfluenzae, Klebsiella pneumoniae, Staphylococcus aureus, or M. catarrhalis.
Use for treatment of acute bacterial sinusitis or acute bacterial exacerbations of chronic bronchitis only when no other treatment options available.Because systemic fluoroquinolones, including moxif..