Mozobil
Generic name:plerixafor [ pler-IX-a-fore ]
Drug classes:Hematopoietic stem cell mobilizer, Other immunostimulants
What is Mozobil?
Mozobil works by helping your bone marrow release stem cells into your bloodstream so they can be collected and transplanted back into the body.
Mozobilis used in people with non-Hodgkin's lymphoma or multiple myeloma.
Mozobil may also be used for purposes not listed in this medication guide.
Warnings
Do not receive Mozobil without telling your doctor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. You should not receive Mozobil if you are allergic to plerixafor, or if you have leukemia.
Before you receive this medicine, tell your doctor if you have kidney disease.
Mozobil is given as an injection in a hospital or clinic setting.
Before receiving Mozobil, you will be given another medication that will help your bone marrow produce stem cells and certain white blood cells that help support your immune system.
To be sure Mozobil is not causing harmful effects, your blood will need to be tested often
Before taking this medicine
You should not be treated with Mozobil if you are allergic to plerixafor, or if you have leukemia.
If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take Mozobil, tell your doctor if you have kidney disease.
Plerixafor may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using Mozobil and for at least 1 week after your last dose. Tell your doctor if you become pregnant.
You may need to have a negative pregnancy test before starting this treatment.
You should not breastfeed while receiving this medication.
How is Mozobil given?
Mozobil is injected under the skin. A healthcare provider will give you this injection.
You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction.
Before receiving Mozobil, you will be given a medication called a granulocyte (GRAN-yoo-loe-site) colony stimulating factor (G-CSF). A G-CSF helps your body produce stem cells and white blood cells to help support your immune system.
Mozobil works together with the G-CSF by causing stem cells and granulocytes produced in the bone marrow to circulate into your bloodstream where they can be collected in blood drawn from your vein.
After your blood is drawn, it will be processed so that the needed stem cells and granulocytes can be separated from other unneeded parts of the blood. These stem cells and granulocytes will then be "transp...
