Nadolol and bendroflumethiazide (Oral)
Medically reviewed by Drugs.com. Last updated on Feb 22, 2022.
Following abrupt cessation of therapy with certain beta-blocking agents, exacerbations of angina pectoris and, in some cases, myocardial infarction have occurred. The dosage should be gradually reduced over 1 to 2 weeks, and the patient should be carefully monitored when discontinuing chronic therapy, particularly in patients with ischemic heart disease. If angina markedly worsens or acute coronary insufficiency develops, nadolol should be reinstated promptly, at least temporarily, and other measures appropriate for the management of unstable angina should be taken. Patients should be warned against interruption or discontinuation of therapy without the physician's advice .
Commonly used brand name(s)
In the U.S.
- Corzide
Available Dosage Forms:
- Tablet
Therapeutic Class: Beta-Adrenergic Blocker, Nonselective/Thiazide Combination
Pharmacologic Class: Beta-Adrenergic Blocker, Nonselective
Chemical Class: Thiazide
Uses for nadolol and bendroflumethiazide
Nadolol and bendroflumethiazide combination is used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Nadolol is a beta-blocker. It works by affecting the response to some nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.
Bendroflumethiazide is a diuretic (water pill). It reduces the amount of water in the body by increasing the flow of urine, which helps lower the blood pressure.
Nadolol and bendroflumethiazide is available only with your doctor's prescription.
Before using nadolol and bendroflumethiazide
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For nadolol and bendroflumethiazide, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to nadolol and bendroflumethiazide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of nadolol and bendroflumethiazide combination in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of nadolol and bendroflumethiazide combination in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caut..
