Naldemedine
Generic name: naldemedine [ nal-DEM-e-deen ]
Brand name: Symproic
Dosage form: oral tablet (0.2 mg)
Drug class:Peripheral opioid receptor antagonists
What is naldemedine?
Naldemedine reduces constipation caused by opioid pain medicine used to treat severe chronic pain.
Naldemedine is for use in adults who use opioid pain medicine to treat chronic pain that is not caused by active cancer.
Naldemedine may also be used for purposes not listed in this medication guide.
Warnings
You should not use naldemedine if you have a blockage in your stomach or intestines.
Stop using naldemedine and call your doctor at once if you have severe stomach pain that does not go away (this can lead to serious medical problems).
Tell your doctor if you have symptoms of opioid withdrawal, such as sweating, feeling hot or cold, tremors, fast heartbeats, agitation, runny nose, watery eyes, vomiting, and diarrhea.
Before taking this medicine
You should not use naldemedine if you are allergic to it, or if you have:
a blockage in your stomach or intestines.
Tell your doctor if you have ever had:
a stomach or intestinal disorder (including Crohn's disease, diverticulitis, or Ogilvie's syndrome);
a stomach ulcer; or
If you use naldemedine while you are pregnant, your baby could have opioid withdrawal symptoms. Tell your doctor if you are pregnant or if you become pregnant.
This medicine may cause opioid withdrawal symptoms in a nursing baby. Do not breast-feed while taking naldemedine, and for at least 3 days after your last dose.
Naldemedine is not approved for use by anyone younger than 18 years old.
How should I take naldemedine?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take naldemedine with or without food.
Call your doctor if your symptoms do not improve, or if they get worse.
Naldemedine may not work as well in people who have been taking opio...
