Naloxegol
Generic name: naloxegol [ nal-OX-ee-gol ]
Brand name: Movantik
Dosage form: oral tablet (12.5 mg; 25 mg)
Drug class:Peripheral opioid receptor antagonists
What is naloxegol?
Naloxegol reduces constipation caused by opioid pain medicine used to treat severe chronic pain. Naloxegol works by treating constipation without reducing the pain-relieving effects of the opioid.
Naloxegol is used in people who have been taking opioid pain medicine for at least 4 weeks, to treat chronic pain that is not caused by cancer.
Naloxegol may also be used for purposes not listed in this medication guide.
Warnings
You should not use naloxegol if you have a blockage in your stomach or intestines.
Tell your doctor if you have symptoms of opioid withdrawal, such as anxiety, feeling irritable, sweating, chills, yawning, stomach pain, and diarrhea.
Stop using naloxegol and call your doctor at once if you have severe stomach pain and/or diarrhea (which can lead to serious medical problems).
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Before taking this medicine
You should not use naloxegol if you are allergic to it, or if you have:
a blockage in your stomach or intestines.
Some medicines can cause unwanted or dangerous effects when used with naloxegol. Your doctor may need to change your treatment plan if you also use:
certain antibiotics;
antifungal medicine;
heart medication; or
antiviral medicine to treat hepatitis C or HIV.
Tell your doctor if you have ever had:
stomach or intestinal problems (including diverticulitis, or ischemic colitis);
stomach cancer, colorectal cancer;
a perforation (a hole or tear) in your esophagus, stomach, or intestines;
recent surgery on the stomach or intestines; or
liver or kidney disease.
If you use naloxegol while you are pregnant, your baby could have opioid withdrawal symptoms. Tell your doctor if you are pregnant or plan to become pregnant.
Do not breastfeed while taking naloxegol.
Naloxegol is not approved for use by anyone you...
