#
Naloxone Injection
  • Drugs A to Z
  • Naloxone (Injection)

Naloxone (Injection)

Medically reviewed by Drugs.com. Last updated on Mar 30, 2022.

Commonly used brand name(s)

In the U.S.

  • Evzio
  • Narcan
  • Zimhi

Available Dosage Forms:

  • Solution

Therapeutic Class: Antidote

Pharmacologic Class: Opioid Antagonist

Uses for naloxone

Naloxone injection is used for emergency treatment of an opioid overdose or a possible overdose. It will temporarily reverse the effects of an opioid medicine. Some signs and symptoms of an opioid emergency are breathing problems (which can range from slow or shallow breathing to no breathing), extreme sleepiness, slow heartbeat, or not being able to respond, a very small (pinpoint) pupil in a person who is difficult to awaken.

Naloxone is available only with your doctor's prescription.

Before using naloxone

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For naloxone, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to naloxone or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of naloxone injection in children.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of naloxone injection in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving naloxone injection.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medic...