Naxitamab
Generic name: naxitamab [ nax-IT-a-mab ]
Brand name: Danyelza
Dosage form: intravenous solution (4 mg/mL)
Drug class:Miscellaneous antineoplastics
What is naxitamab?
Naxitamab in used to treat high-risk neuroblastoma (a rare form of cancer) in adults and children at least 1 year old.
Naxitamab is used in combination with another medicine that causes your body to produce certain blood cells that help fight the cancer and protect you from infection.
Naxitamab is given after other cancer treatments did not work well, or have stopped working.
Naxitamab was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to naxitamab, but further studies are needed.
Naxitamab may also be used for purposes not listed in this medication guide.
Warnings
Naxitamab can cause serious side effects. Call your doctor at once if you have pain or a severe headache, numbness or tingling, weakness, problems with speech or thought, vision problems, painful urination, fast or pounding heartbeats, chest pain, or a seizure.
Tell your caregiver if you have any of these side effects during the injection: feeling dizzy or light-headed, itching, warmth or tingling, shortness of breath, noisy breathing, or swelling in your face.
Before taking this medicine
You should not be treated with naxitamab if you are allergic to it.
Tell your doctor if you have ever had high blood pressure.
You may need to have a negative pregnancy test before starting this treatment.
Do not use naxitamab if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using naxitamab and for at least 2 months after your last dose.
Do not breastfeed while using this medicine, and for at least 2 months after your last dose.
How is naxitamab given?
Naxitamab is given as an infusion into a vein. A healthcare provider will give you this injection.
This medicine must be given slowly, and the infusion can take 30 to 60 minutes to complete.
Naxitamab is usually given in a 28-day treatment cycle, repeated every 4 or 8 weeks. You may need to use the medicine only during the first week of each cycle. Your doctor will determine how long to treat you with this medicine.
You may be given other medications to help prevent serious side effects or an allergic reaction. Keep using these medicines for as long as your doctor has prescribed.
You will be watched closely for at least 2 hours after the injection to make sure you do not ha...
