Generic name:neratinib [ ne-RA-ti-nib ]
Drug classes:EGFR inhibitors, HER2 inhibitors
What is Nerlynx?
Nerlynx is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
Nerlynx is used alone or with other medicines to treat early-stage HER2-positive breast cancer. Nerlynx is also used to treat HER2-positive breast cancer that is advanced or has spread to other parts of the body (metastatic).
Nerlynx is used for breast cancer only if your tumor tests positive for a protein called human epidermal growth factor receptor 2 (HER2). HER2 protein can speed the growth of cancer cells.
Nerlynx is usually given after you have been treated with another medicine called trastuzumab (Herceptin).
Warnings
Nerlynx can cause severe diarrhea, which can be life-threatening if it leads to dehydration. You may be given anti-diarrhea medications for the first 2 months of treatment with Nerlynx.
Call your doctor if you are sick with severe diarrhea, or you also have weakness, dizziness, or a fever.
Before taking this medicine
To make sure Nerlynx is safe for you, tell your doctor if you have ever had:
You may need to have a negative pregnancy test before starting this treatment.
Neratinib can harm an unborn baby or cause birth defects if the mother or the father is using this medicine.
If you are a woman, do not use Nerlynx if you are pregnant. Use effective birth control to ...
