Netupitant and palonosetron
Generic name: netupitant and palonosetron (oral) [ net-UE-pi-tant-and-PAL-oh-NOE-se-tron ]
Brand name: Akynzeo
Dosage form: oral capsule (300 mg-0.5 mg)
Drug class:Miscellaneous antiemetics
What is netupitant and palonosetron?
Netupitant and palonosetron is a combination medicine used to help prevent nausea and vomiting caused by chemotherapy. netupitant and palonosetron is given together with a steroid called dexamethasone.
Netupitant and palonosetron helps prevent nausea and vomiting that occurs both during chemotherapy and later on (delayed nausea and vomiting).
Netupitant and palonosetron may also be used for purposes not listed in this medication guide.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
Netupitant and palonosetron is not approved for use by anyone younger than 18 years old.
Tell your doctor if you have ever had:
liver or kidney disease; or
an allergic reaction to a medicine for nausea or vomiting, such as dolasetron (Anzemet), ondansetron (Zofran), or palonosetron (Aloxi).
Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, or serious infections. These medicines may interact with netupitant and palonosetron and cause a serious condition called serotonin syndrome.
Netupitant and palonosetron may harm an unborn baby. Tell your doctor if you become pregnant.
You should not breast-feed while using netupitant and palonosetron.
How should I take netupitant and palonosetron?
This medicine is given ahead of time and will not treat nausea or vomiting you already have.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
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