Generic name:bempedoic acid and ezetimibe (tablets)
Drug class:Antihyperlipidemic combinations
What is Nexlizet?
Nexlizet is a prescription medicine that contains two cholesterol lowering medicines: bempedoic acid and ezetimibe. Nexlizet is used along with diet and other lipid-lowering medicines in the treatment of adults with:
- heterozygous familial hypercholesterolemia (HeFH). HeFH is an inherited condition that causes high levels of “bad” cholesterol called low density lipoprotein (LDL).
- known heart disease who need additional lowering of “bad” cholesterol (LDL-C) levels.
It is not known if Nexlizet can decrease problems from high cholesterol, such as heart attacks, stroke, death, or other heart problems.
It is not known if Nexlizet is safe and effective in people with severe kidney problems including people with end-stage kidney disease who are on dialysis.
It is not known if Nexlizet is safe and effective in people with moderate to severe liver problems.
It is not known if Nexlizet is safe and effective in children under 18 years of age.
Who should not take Nexlizet?
You should not take Nexlizet if you are allergic to ezetimibe tablets. Ezetimibe, one of the active ingredients in Nexlizet, can cause serious allergic reactions such as anaphylaxis, angioedema, rash, and urticaria. Stop taking Nexlizet, call your healthcare provider or go to the nearest hospital emergency room right away if you have any signs or symptoms of an allergic reaction including:
- swelling of your face, lips, mouth or tongue
- wheezing
- severe itching
- fast heart beat or pounding in your chest
- trouble breathing
- dizziness or fainting
See the end of this leaflet for a complete list of ingredients.
Before taking Nexlizet
Before you start taking Nexlizet, tell your healthcare provider about all your medical conditions, including
