Generic name:avalglucosidase alfa [ AY-val-gloo-KOE-si-dase-AL-fa ]
Drug class:Lysosomal enzymes
What is Nexviazyme?
Nexviazyme helps replace an enzyme that is missing in people with a genetic disorder called late-onset Pompe disease, (also called GAA deficiency) in children at least 1 year old.
Nexviazyme may also be used for purposes not listed in this medication guide.
Warnings
Tell your caregivers or get emergency medical help right away if you have any signs of a severe allergic reaction, such as itching, rash, redness or tingling, chest discomfort, wheezing, trouble breathing or swallowing, swelling in your face, pale skin, and blue lips or fingernails.
Before taking this medicine
Tell your doctor if you have ever had:
heart disease; or
lung disease or breathing problems.
Tell your doctor if you are pregnant or plan to become pregnant. Having untreated Pompe disease during pregnancy may increase your risk of worsened breathing problems and joint or muscle problems. The benefit of treating Pompe disease may outweigh any risks.
Ask a doctor if it is safe to breastfeed while using Nexviazyme.
Your name may be listed on the Pompe Registry. This is to track the progress of your disease and the outcome of your treatment with Nexviazyme.
How is Nexviazyme given?
Avalglucosidase is injected into a vein by a healthcare provider, usually once every 2 weeks.
This medicine must be given slowly over 4 to 5 hours.
You may be given other medications to help prevent serious side effects or allergic reaction. Keep taking these medicines for as long as your...
