Anifrolumab
Generic name: anifrolumab [ AN-i-FROL-ue-mab ]
Brand name: Saphnelo
Dosage form: intravenous solution (fnia 300 mg/2 mL)
Drug class:Selective immunosuppressants
What is anifrolumab?
Anifrolumab is used to treat moderate to severe systemic lupus erythematosus (SLE) in adults who already receive standard treatment for SLE.
Anifrolumab may also be used for purposes not listed in this medication guide.
Warnings
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
Before taking this medicine
You should not be treated with anifrolumab if you are allergic to it.
Tell your doctor if you have ever had:
an active or chronic infection;
cancer;
treatment with a biologic medicine or monoclonal antibody; or
if you are scheduled to receive a vaccine.
Make sure you are current on all vaccines before you start using anifrolumab.
Tell your doctor if you are pregnant or you become pregnant, or if you are breastfeeding.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of anifrolumab on the baby.
Anifrolumab may affect your baby's immune system, but having SLE during pregnancy may cause complications such as worsened lupus, eclampsia (dangerously high blood pressure), premature birth, miscarriage, or growth problems in the unborn baby. SLE in the mother may also cause lupus or heart problems to develop in the newborn. The benefit of treating SLE may outweigh any risks to the baby.
Not approved for use by anyone younger than 18 years old.
How is anifrolumab given?
Anifrolumab is injected into a vein by a healthcare provider, usually once ever 4 weeks.
anifrolumab must be given slowly over 30 minutes.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your anifrolumab injection.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while receiving anifrolumab?
Avoid receiving a "live" vaccine. The vaccine may not work as well while you are using anifrolumab. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).
Anifrolumab side effects
Get emergency medical help ...
