Anifrolumab-fnia (Intravenous)

Medically reviewed by Drugs.com. Last updated on Apr 28, 2022.

Commonly used brand name(s)

In the U.S.

• Saphnelo

Available Dosage Forms:

• Solution

Therapeutic Class: Immunological Agent

Pharmacologic Class: Anifrolumab

Uses for anifrolumab-fnia

Anifrolumab-fnia injection is used to treat moderate to severe systemic lupus erythematosus (SLE) in patients who are also receiving other lupus treatments. It is a monoclonal antibody that changes the immune system to help control lupus symptoms.

Anifrolumab-fnia is available only with your doctor's prescription.

Before using anifrolumab-fnia

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For anifrolumab-fnia, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to anifrolumab-fnia or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of anifrolumab-fnia injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of anifrolumab-fnia injection in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving anifrolumab-fnia, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using anifrolumab-fnia with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abatacept
• Adalimumab
• Adenovirus Vaccine, Live
• Alefacept
• Anakinra
• Bacillus of Calmette and Guerin Vaccine, Live
• Brodalumab
• Certolizumab Pegol
• Cholera Vaccine, Live
• Dengue Tetravalent Vaccine, Live
• Ebola Zaire Vaccine, Live
• Etanercept
• Golimumab
• Guselkumab
• Infliximab
• Influenza Virus Vaccine, Live
• Ixekizumab
• Measles Virus Vaccine, Live
• Mumps Virus Vaccine, Live
• Natalizumab
• Poliovirus Vaccine, Live
• Risankizumab
• Rituximab
• Rotavirus Vaccine, Live
• Rubella Virus Vaccine, Live
• Sarilumab
• Secukinumab