Acetaminophen and pseudoephedrine

Generic name: acetaminophen and pseudoephedrine [ a-SEET-a-MIN-oh-fen-and-SOO-doe-ee-FED-rin ]
Brand names: Alka-Seltzer Cold and Sinus, Allerest No Drowsiness, Bayer Select Decongestant, Benadryl Allergy Sinus Headache, Dristan Cold Non-Drowsy, ... show all 35 brands Ornex, Ornex Maximum Strength, Sinarest Sinus, Sine-Off Maximum Strength, Tavist Sinus, Triaminic Softchews Allergy Sinus, Bayer Select Sinus Pain Formula, Sudafed Sinus, Contac Sinus, Sinutab Regular Strength, Tylenol Sinus Maximum Strength, Excedrin Sinus, Genapap Sinus, Mapap Sinus, Suphedrin Plus, Phenapap, Pseudoephedrine Sinus, Sinutab Maximum Strength, Sinus Maximum Strength, Tylenol Cold Infants, Suphedrin Sinus, Theraflu Sinus, Sudafed Cold and Sinus, Sudogest Sinus Maximum Strength, Children's Tylenol Sinus, Tylenol Sinus Childrens, Sudafed Sinus Headache, Sinutab Maximum Strength Non Drowsy, Tylenol Sinus Gelcap, Nexafed Sinus Pressure + Pain
Dosage forms: oral capsule (325 mg-30 mg); oral tablet (325 mg-30 mg; 500 mg-30 mg); oral tablet, chewable (160 mg-15 mg)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Jul 28, 2021. Written by Cerner Multum.

What is acetaminophen and pseudoephedrine?

Acetaminophen is a pain reliever and a fever reducer.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Acetaminophen and pseudoephedrine is a combination medicine used to treat headache, fever, body aches, stuffy nose, and sinus congestion caused by allergies, the common cold, or the flu.

Acetaminophen and pseudoephedrine may also be used for purposes not listed in this medication guide.

Warnings

Ask a doctor before taking medicine that contains acetaminophen if you have ever had liver disease, or if you drink more than 3 alcoholic beverages per day.

You should not use acetaminophen and pseudoephedrine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid.

Avoid drinking alcohol. It may increase your ris