Generic name:flurandrenolide
Dosage form: cream
Drug class:Topical steroids
Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.
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NOLIX
Flurandrenolide Cream USP, 0.05%
Rx only
Nolix Cream Description
NOLIX ™ Cream (flurandrenolide USP, 0.05%) is a potent corticosteroid intended for topical use. Flurandrenolide occurs as white to off-white, fluffy, crystalline powder and is odorless. Flurandrenolide is practically insoluble in water and in ether. One g dissolves in 72 mL of alcohol and in 10 mL of chloroform. The molecular weight of flurandrenolide is 436.52.
The chemical name of flurandrenolide is Pregn-4-ene-3,20-dione,6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α, 11β, 16α)-; its empirical formula is C 24H 33FO 6.
The structure is as follows:
Each gram of NOLIX ™ Cream contains 0.5 mg (1.145 μmol; 0.05%) flurandrenolide in an emulsified base composed of cetyl alcohol, citric acid, mineral oil, polyoxyl 40 stearate, propylene glycol, sodium citrate, stearic acid, and purified water.
