Novacort

Generic name:hydrocortisone acetate and pramoxine hydrochloride
Drug class:Anorectal preparations

Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Prescribing Information

Novacort®gel

Novacort Description

Each gram of Novacort contains 2.0% (20 mg) Hydrocortisone Acetate and 1.0% (10 mg) Pramoxine Hydrochloride (HCI). Other Ingredients: Aloe Polysaccharide, Benzyl Alcohol, Biopeptide CL, Cetyl Alcohol, Dimethicone, Dimethyl Isosorbide, Glycerin, Glyceryl Stearate, Hydroxypropyl Methylcellulose, PEG-100 Stearate, Phenoxyethanol, Poloxamer 407, Propylene Glycol, Purified Water, Stearoxytrimethylsilane, Stearyl Alcohol, and Witch Hazel Distillate.

Hydrocortisone Acetate
Hydrocortisone Acetate is a topical corticosteroid anti-inflammatory and anti-pruritic agent. Chemically, Hydrocortisone Acetate is [Pregn-4-ene-3, 20-dione, 21-(acetyloxy)-11, 17-dihydroxy-, (11-beta)-C23H32O6] with a molecular weight of 404.50. Chemically, Hydrocortisone Acetate is represented by the following structural formula:

Pramoxine Hydrochloride
Pramoxine Hydrochloride (Pramoxine HCl) is a topical anesthetic agent. Chemically, Pramoxine Hydrochloride is [4-(3-(p-butoxyphenoxy)propyl) morpholine Hydrochloride

C17H27NO3. • HCI] with a molecular weight of 329.87. Chemically, Pramoxine Hydrochloride is represented by the following structural formula:

Novacort - Clinical Pharmacology

Topical corticosteroids share anti-inflammatory, anti-pruritic, and vasoconstrictive actions.