NyQuil D

Generic name:acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine [ a-SEET-a-MIN-o-fen, DEX-troe-meth-OR-fan, dox-IL-a-meen, SOO-doe-e-FED-rin ]
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Feb 16, 2022. Written by Cerner Multum.

What is NyQuil D?

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the cough reflex in the brain that triggers coughing.

Doxylamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

NyQuil D is a combination medicine used to treat headache, fever, body aches, cough, runny nose, sneezing, and sinus congestion caused by the common cold, or the flu.

NyQuil D will not treat a cough that is caused by smoking, asthma, or emphysema.

NyQuil D may also be used for purposes not listed in this medication guide.

Warnings

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).

In rare cases, acetaminophen may cause a severe skin reaction. Stop taking this medicine and call yo...