Dosage form: vaginal insert
Drug classes:Mouth and throat products, Polyenes
Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.
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Nystatin Vaginal Insert Description
Nystatin is an antimycotic polyene antibiotic obtained from Streptomyces noursei.
Nystatin Vaginal Inserts, USP are available as oval-shaped compressed inserts for intravaginal administration, each containing 100,000 units Nystatin, USP. Inactive ingredients include corn starch, ethylcellulose, anhydrous lactose, microcrystalline cellulose, polyethylene glycol and stearic acid.
Nystatin Vaginal Insert - Clinical Pharmacology
Nystatin is both fungi-static and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi. Nystatin acts by binding to sterols in the cell membrane of sensitive fungi with a resultant change in membrane permeability allowing leakage of intracellular components. Nystatin exhibits no appreciable activity against bacteria, protozoa, trichomonads or viruses.
Nystatin is not absorbed from intact skin or mucous membranes.
Indications and Usage for Nystatin Vaginal Insert
Nystatin Vaginal Inserts, USP are effective for the local treatm...