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Ocrevus
  • Treatments
  • Multiple Sclerosis

Ocrevus

Generic name:ocrelizumabOK-re-LIZ-ue-mab ]
Drug class:CD20 monoclonal antibodies

Medically reviewed by Philip Thornton, DipPharm. Last updated on May 5, 2021.

What is Ocrevus?

Ocrevus is a monoclonal antibody that affects the actions of the body's immune system. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.

Ocrevus is used to treat primary progressive multiple sclerosis and relapsing forms of multiple sclerosis in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).

Ocrevus may also be used for purposes not listed in this medication guide.

Warnings

Ocrevus may cause unpleasant side effects. Some side effects may occur during the injection or up to 24 hours later. Tell your caregiver if you feel dizzy, nauseated, itchy, or have chest tightness, throat irritation, or trouble breathing,.

Ocrevus affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, cough, mouth sores, skin sores or blisters, itching, tingling, burning pain, or problems with speech, thought, vision, or muscle movement.

If you've ever had hepatitis B, it may become active or get worse while you are using or after you stop using ocrelizumab. You may need frequent liver function tests for several months.

Before taking this medicine

You should not be treated with Ocrevus if you are allergic to ocrelizumab, or if you have:

  • active infection with hepatitis B.

Your doctor may perform tests to make sure you do not have hepatitis B or other infections.

You should not re...