Anticoagulant Citrate Dextrose A

Generic name: anhydrous citric acid, dextrose monohydrate, and trisodium citrate dihydrate
Dosage form: solution

Description

Anticoagulant Citrate Dextrose Solution, Solution A, U.S.P., (ACD-A), is a sterile, non-pyrogenic solution of citric acid, sodium citrate, and dextrose, in water for injection. Each 10 mL of solution contains:

Single patient use only, on a single occasion.

Clinical Pharmacology

ACD-A acts as an anticoagulant by the action of the citrate ion chelating free ionized calcium, thus making calcium unavailable to the coagulation system.

Indications and Usage

Anticoagulant Citrate Dextrose Solution, Solution A, U.S.P. (ACD-A), is intended for use as an anticoagulant in the extracorporeal blood processing with Autologous PRP Systems in production of platelet rich plasma (PRP). Refer to the manufacturer's Operator's Manual of the Autologous PRP System for the Directions for Use.

Contraindications

NOT FOR DIRECT INTRAVENOUS INFUSION

Warnings

NOT FOR DIRECT INTRAVENOUS INFUSION

Precautions

General

• Aseptic technique must be maintained at all times.
• ACD-A solution is a clear and colorless solution. If the product shows any cloudiness or turbidity, the product should be discarded.
• The closure system provides a biological barrier and should be intact – discard product if system is compromised.

Information for Patients

None.

Carcinogenesis, mutagenesis, impairment of fertility

Lon...