Ofev
Generic name:nintedanib [ nin-TED-a-nib ]
Drug class:Multikinase inhibitors
What is Ofev?
Ofev is used in people with diseases that cause scar tissue (fibrosis) to form deep within the lungs. The scar tissue thickens and becomes stiff over time, which can make it harder for your lungs to work. Decreased lung function can make it hard for you to breathe. Other medical problems can occur when your brain, heart, and other organs do not get enough oxygen.
Ofev is used to treat a lung disease called idiopathic pulmonary fibrosis (IPF).
Ofev is also used to treat chronic (long lasting) interstitial lung disease in which the scar tissue keeps getting worse.
Ofev is also used to slow the decline in lung function in people with a disorder called systemic sclerosis-associated interstitial lung disease (sometimes called scleroderma-associated ILD).
Ofev is not a cure for IPF or ILD, but this medicine can slow the effects of these diseases on your lungs.
Warnings
Ofev can cause birth defects or death in an unborn baby. Avoid getting pregnant while you are using this medicine and for at least 3 months after your last dose. Use effective birth control, with an extra barrier method (condom, diaphragm, cervical cap, contraceptive sponge).
Before taking this medicine
To make sure Ofev is safe for you, tell your doctor if you have ever had:
heart problems;
a blood clot;
bleeding problems (in you or a family member);
surgery on your stomach or intestines;
if you smoke; or
if you take a blood thinner such as warfarin (Coumadin, Jantoven).
You may need to have a negative pregnancy test before starting this treatment.
Nintedanib can cause birth defects or death in an unborn a baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
If you use hormonal birth control (birth control pills, injections, implants, skin patches, or vaginal rings), also use a barrier form of birth control to prevent pregnancy while taking Ofev. Barrier forms include a condom, diaphragm, cervical cap, or contraceptive sponge).
Ofev may affect fertility (your ability to have children) in women. However, it is important to use birth control to prevent pregnancy because this medicine can harm an unborn baby.
You should not breastfeed while using this medicine.
Ofev is not approved for use by anyone younger than 18 years...