Generic name:ruxolitinib
Dosage form: cream for topical use
Drug class:Topical antineoplastics
What is Opzelura?
Opzelura is a prescription medicine used on the skin (topical) for short-term and non-continuous treatment of mild to moderate eczema (atopic dermatitis) in non-immunocompromised people 12 and older whose disease:
- is not well controlled with topical prescription therapies or
- when those therapies are not recommended
The use of Opzelura along with therapeutic biologics for atopic dermatitis, other JAK inhibitors, or strong immunosuppressants such as azathioprine or cyclosporine is not recommended.
It is not known if this medicine is safe or effective in children less than 12 years of age.
Important information
Opzelura cream is for use on the skin only. Do not use Opzelura cream, in your eyes, mouth or vagina.
Opzelura may cause serious side effects, including:
- Serious Infections. Opzelura contains ruxolitinib. Ruxolitinib belongs to a class of medicines called Janus kinase (JAK) inhibitors. JAK inhibitors are medicines that affect your immune system. JAK inhibitors can lower the ability of your immune system to fight infections. Some people have had serious infections while taking JAK inhibitors by mouth, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses that can spread throughout the body. Some people have been hospitalized or died from these infections. Some people have had serious infections of their lungs while taking Opzelura.
- Your healthcare provider should watch you closely for signs and symptoms of TB during treatment.
Opzelura should not be used in people with an active, serious infection, including localized infections. You should not start treatment if you have any kind of infection unless your healthcare provider tells you it is okay. You may be at ..
