Generic name:elagolix [ EL-a-GOE-lix ]
Drug class:Gonadotropin-releasing hormone antagonists
Medically reviewed by Drugs.com. Last updated on Apr 20, 2022.
What is Orilissa?
Orilissa binds to the same receptors in the body as a certain hormone that stimulates the production of sex hormones.
Orilissa works by lowering blood levels of estradiol and progesterone (female sex hormones).
Orilissa is used to treat moderate to severe pain caused by endometriosis.
Warnings
Do not use Orilissa if you are pregnant. Elagolix may cause miscarriage.
Hormonal birth control methods (birth control pills, injections, implants) could make Orilissa less effective. Use a condom or diaphragm with spermicide while you are taking elagolix and for at least 1 week after your last dose.
Elagolix can lower your estrogen levels, which may cause bone loss (osteoporosis). Talk with your doctor about ways to keep your bones healthy during and after treatment with this medicine.
Before taking this medicine
You should not use Orilissa if you are allergic to elagolix, or if:
you have osteoporosis;
you are pregnant or may become pregnant;
you have severe liver disease; or
you also use certain other medicines such as cyclosporine, gemfibrozil, or rifampin.
You may need to have a negative pregnancy test before starting this treatment.
Do not use Orilissa if you are pregnant, and tell yo...
