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Ozanimod
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Ozanimod

Generic name: ozanimod [ oh-ZAN-i-mod ]
Brand name: Zeposia
Dosage form: oral capsule (0.23 mg-0.46 mg; 0.23 mg-0.46 mg-0.92 mg; 0.92 mg)
Drug class:Selective immunosuppressants

Medically reviewed by Judith Stewart, BPharm. Last updated on Aug 9, 2021.

What is ozanimod?

Ozanimod is used to treat relapsing forms of multiple sclerosis in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).

Ozanimod is used only if you have a specific genotype. Your doctor will test you for this genotype.

Ozanimod is also used to treat adults with moderately to severely active ulcerative colitis.

It is not known if this medicine is safe and effective in children.

Warnings

You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, flu symptoms, feeling very tired, cough, rash, painful and frequent urination, neck stiffness, increased sensitivity to light. Your risk of infection could last for 3 months after you stop taking ozanimod.

You should not use ozanimod if you have a serious heart condition such as "AV block" or sick sinus syndrome and no pacemaker, or if you've recently had heart failure, a heart rhythm disorder, chest pain, heart attack, or stroke. You also should not use ozanimod if you have severe untreated sleep apnea.

Do not use ozanimod if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Wait at least 14 days after stopping an MAO inhibitor before you take this medicine.

Ozanimod can slow your heart rate when you start taking it. Tell your doctor if you have slow heartbeats, chest pain, shortness of breath, feeling like your heart is skipping beats.

You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, aches, tiredness, cough, rash, painful and frequent urination, confusion, neck stiffness, or increased sensitivity to light. Your risk of infection could last for 3 months after you stop taking this medicine.

Before taking this medicine

You should not use ozanimod if you are allergic to it, or if you have certain serious heart conditions, especially:

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