Paliperidone (injection)

Generic name: paliperidone (injection) [ PAL-ee-PER-i-DONE ]
Brand names: Invega Sustenna, Invega Trinza
Dosage form: intramuscular suspension, extended release (117 mg/0.75 mL; 156 mg/mL; 234 mg/1.5 mL; 273 mg/0.88 mL; 39 mg/0.25 mL; 410 mg/1.32 mL; 546 mg/1.75 mL; 78 mg/0.5 mL; 819 mg/2.63 mL)
Drug class:Atypical antipsychotics

Medically reviewed by Drugs.com on Jan 26, 2022. Written by Cerner Multum.

What is paliperidone?

Paliperidone is an antipsychotic medicine that is used to treat schizophrenia in adults. Paliperidone is also used alone or with other medicines to treat schizoaffective disorder in adults.

Paliperidone may also be used for purposes not listed in this medication guide.

Warnings

Paliperidone is not approved for use in older adults with dementia-related psychosis.

Before taking this medicine

You should not use paliperidone if you are allergic to paliperidone or to risperidone (Risperdal).

Paliperidone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.

High doses or long-term use of paliperidone can cause a serious movement disorder that may not be reversible. The longer you use paliperidone, the more likely you are to develop this disorder, especially if you are a woman or an older adult.

Before you receive your first injection, tell your doctor if you have never taken oral (by mouth) paliperidone or risperidone.

Tell your doctor if...