Pegfilgrastim-apgf (Subcutaneous)
Medically reviewed by Drugs.com. Last updated on May 9, 2022.
Commonly used brand name(s)
In the U.S.
- Nyvepria
Available Dosage Forms:
- Solution
Therapeutic Class: Hematopoietic
Pharmacologic Class: Pegfilgrastim
Uses for pegfilgrastim-apgf
Pegfilgrastim-apgf injection is used to treat neutropenia (low white blood cells) that is caused by cancer medicines. It is a synthetic (man-made) form of a substance that is naturally produced in your body called a colony stimulating factor. Pegfilgrastim-apgf helps the bone marrow to make new white blood cells.
When certain cancer medicines are used to fight cancer cells, they also affect the white blood cells that fight infections. Pegfilgrastim-apgf is used to reduce the risk of infection while you are being treated with cancer medicines.
Pegfilgrastim-apgf is available only with your doctor's prescription.
Before using pegfilgrastim-apgf
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For pegfilgrastim-apgf, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to pegfilgrastim-apgf or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of pegfilgrastim-apgf injection in the pediatric population.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of pegfilgrastim-apgf in the elderly.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of pegfilgrastim-apgf. Make sure you tell your doctor if you have any other medical problems, especially:
- Bone marrow problems (eg, bone marrow cancer, myelodysplasia) or
- Glomerulonephritis (kidney disease) or
- Leukocytosis (high white blood cell count) or
- Lung disease or breathing problems or ...