Generic name:pemigatinib [ PEM-i-GA-ti-nib ]
Drug class:Multikinase inhibitors
What is Pemazyre?
Pemazyre is a kinase inhibitor that blocks the action of protein kinases.
Pemazyre a prescription medicine used in adults to treat bile duct cancer that has spread to other parts of the body (metastatic) or cannot be removed with surgery. This medicine is usually given after your cancer has been treated with another medicine.
Pemazyre is used only if your cancer has a specific genetic marker (an abnormal "FGFR2" gene). Your doctor will test you for this gene.
Pemazyre was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to Pemazyre, but further studies are needed.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
To make sure Pemazyre is safe for you, tell your doctor if you have ever had:
problems with your eyes;
vision problems; or
trouble swallowing pills.
You may need to have a negative pregnancy test before starting this treatment.
Both men and women using Pemazyre should use effective birth control to prevent pregnancy. Pemazyre can harm an unborn baby or cause a miscarriage if the mother or father is using this medicine.
Keep using birth control for at least 1 week after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Pemazyre.
Do not breastfeed while using this...
