Generic name:pemetrexed (intravenous route) [ pem-e-TREX-ed ]
Drug class:Antimetabolites
Medically reviewed by Drugs.com. Last updated on Dec 24, 2021.
Commonly used brand name(s)
In the U.S.
- Alimta
- Pemfexy
Available Dosage Forms:
- Solution
- Powder for Solution
Therapeutic Class: Antineoplastic Agent
Uses for Pemfexy
Pemetrexed injection is used in combination with pembrolizumab and platinum cancer medicines to treat metastatic (cancer that has spread) non-squamous non-small cell lung cancer (NSCLC) with no EGFR or ALK gene mutations. It is also used together with cisplatin to treat advanced or metastatic, non-squamous NSCLC.
Pemetrexed injection is also used as maintenance treatment of advanced or metastatic NSCLC that has not progressed after a previous 4-cycle treatment with platinum cancer medicines. It is also used to treat metastatic non-squamous NSCLC that has come back after a previous chemotherapy.
Pemetrexed injection is also used together with cisplatin to treat malignant pleural mesothelioma (cancer that affects the inside lining of the lungs and chest wall) that cannot be removed by surgery. Pemetrexed belongs to the group of medicines called antineoplastics.
This medicine is given only by or under the direct supervision of your doctor.
Before using Pemfexy
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies on the relationship of age to the effects of pemetrexed injection have not been perform...
