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Penicillin G Procaine
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  • FDA PI

Penicillin G Procaine

Dosage form: injection, suspension

Medically reviewed by Drugs.com. Last updated on Jul 1, 2021.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Penicillin G Procaine and other antibacterial drugs, Penicillin G Procaine should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

Prior to administration of the drug, carefully read the WARNINGS, ADVERSE REACTIONS, and DOSAGE AND ADMINISTRATION sections of the labeling.

Rx only

Penicillin G Procaine Description

This product is designed to provide a stable aqueous suspension of Penicillin G Procaine, ready for immediate use. This eliminates the necessity for addition of any diluent, required for the usual dry formulation of injectable penicillin.

Penicillin G Procaine is chemically designated as (2S, 5R, 6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid compound with 2-(diethylamino)ethyl p-aminobenzoate (1:1) monohydrate.

Its molecular formula is C16H18N2O4S∙C13H20N2O2∙H2O with a molecular weight of 588.72. Its structural formula is as follows:

Each syringe, 1,200,000 units (2 mL size) or 600,000 units (1 mL size), contains Penicillin G Procaine in a stabilized aqueous suspension with sodium citrate buffer; and as w/v, approximately 0.5% lecithin, 0.5% carboxymethylcellulose, 0.5% povidone, 0.1% methylparaben, and 0.01% propylparaben.

Penicillin G Procaine Injectable Suspension is viscous and opaque. Read CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, and