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Penicillin V
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Penicillin V

Generic name: penicillin V [ pen-i-SILL-in ]
Brand names: PC Pen VK, Pen-V
Drug class:Natural penicillins

Medically reviewed by Melisa Puckey, BPharm. Last updated on May 13, 2022.

What is penicillin V?

Penicillins are a group of antibiotics that fight bacteria and was originally developed from the Penicillium fungi.   Penicillin V is one type of penicillin antibiotic and is used to treat a wide range of bacterial infections such as ear infections, throat infections, skin infections and preventing rheumatic fever.

It should only used if the bacterial infection is sensitive to penicillin V.

Penicillin V may also be used for other purposes not listed in this medication guide.

Warnings

Do not use this medication if you are allergic to penicillin V or to any other penicillin antibiotic, such as amoxicillin (Amoxil), ampicillin (Omnipen, Principen), carbenicillin (Geocillin), dicloxacillin (Dycill, Dynapen), or oxacillin (Bactocill).

Before using penicillin V, tell your doctor if you are allergic to cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others, or if you have asthma, kidney disease, a bleeding or blood clotting disorder, a history of diarrhea caused by taking antibiotics, or a history of any type of allergy.

Penicillin V can make birth control pills less effective, which may result in pregnancy. Before taking this medicine, tell your doctor if you use birth control pills. Take penicillin V for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Penicillin V will not treat a viral infection such as the common cold or flu. Do not give this medication to another person, even if they have the same symptoms you do.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Before taking this medicine

Do not use this medication if you are allergic to penicillin V or to any other penicillin antibiotic, such as:

  • amoxicillin (Amoxil, Amoxicot, Biomox, Dispermox, Trimox);

  • ampicillin (Omnipen, Principen);

  • carbenicillin (Geocillin);

  • dicloxacillin (Dycill, Dynapen); or

  • oxacillin (Bactocill).

Before using penicillin V, tell your doctor if you are allergic to any drugs (especially cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others), or if you have:

  • asthma;

  • kidney disease;

  • a bleeding or blood clotting disorder;

  • a history of diarrhea caused by taking antibiotics; or

  • a history of any type of allergy.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take penicillin V.

FDA pregnancy category B. Penicillin V is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to...