Pennsaid

Generic name:diclofenac topical [ dye-KLOE-fen-ak-TOP-ik-al ]
Drug class:Topical non-steroidal anti-inflammatories

Medically reviewed by Kaci Durbin, MD. Last updated on Jun 7, 2022.

What is Pennsaid?

Pennsaid is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing substances in the body that cause pain and inflammation.

Pennsaid (diclofenac topical 2% solution) is used to treat pain in the knees caused by osteoarthritis.

Pennsaid is for use only on the knees and should not be used on other parts of the body.

Warnings

Pennsaid can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease.

Pennsaid may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.

Before taking this medicine

Do not use Pennsaid just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Diclofenac can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while using.

You should not use Pennsaid if you are allergic to diclofenac (Voltaren, Cataflam, Flector, and others)

Do not use Pennsaid if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

To make sure Pennsaid is safe for you, tell your doctor if you have:

• heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;

• a history of heart attack, stroke, or blood clot;

• a history of stomach ulcers or bleeding;

• asthma;

• liver or kidney disease; or...