Perjeta

Generic name:pertuzumab [ per-TOO-zoo-mab ]
Drug class:HER2 inhibitors

Medically reviewed by Philip Thornton, DipPharm. Last updated on May 23, 2022.

What is Perjeta?

Perjeta is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Perjeta is used together with other cancer medicines (trastuzumab and docetaxel) to treat HER2-positive breast cancer.

Perjeta may also be used for purposes not listed in this medication guide.

Warnings

Perjeta can cause birth defects or death to the unborn baby. Do not use if you are pregnant. Avoid getting pregnant while using this medicine and for at least 7 months after your last dose.

Perjeta can cause life-threatening heart problems. Your heart function may need to be checked before you start using this medicine and during your treatment.

Call your doctor at once if you have new or worsening cough, shortness of breath, or swelling in your lower legs.

Before taking this medicine

Do not use Perjeta if you are allergic to pertuzumab, or if you are pregnant or breastfeeding.

Tell your doctor if you have ever had:

• heart disease, congestive heart failure, heart rhythm disorder;

• untreated or uncontrolled high blood pressure (hypertension);

• a heart attack; or

• radiation treatment in your chest area.

Do not use Perjeta if you are pregnant. It can cause birth defects or death to the unborn baby. Use effective birth control to prevent pregnancy while you are using pertuzumab with trastuzumab, and for at least 7 months after your treatment ends. Tell your doctor right away if you become pregnant.

If you are pregnant,...