Phenylephrine and ketorolac (Ophthalmic)

Medically reviewed by Drugs.com. Last updated on Mar 6, 2022.

Commonly used brand name(s)

In the U.S.

• Omidria

Available Dosage Forms:

• Solution

Therapeutic Class: Mydriatic-Cycloplegic

Pharmacologic Class: NSAID

Chemical Class: Acetic Acid (class)

Uses for phenylephrine and ketorolac

Ketorolac and phenylephrine ophthalmic solution is combined with an eye irrigation solution used during cataract surgery or intraocular lens replacement. This is to maintain pupil size by preventing intraoperative miosis (pupil constriction) and to reduce pain after eye surgery.

Phenylephrine and ketorolac is to be given only by or under the direct supervision of your eye doctor (ophthalmologist).

Before using phenylephrine and ketorolac

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For phenylephrine and ketorolac, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to phenylephrine and ketorolac or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of ketorolac and phenylephrine ophthalmic solution in the pediatric population.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ketorolac and phenylephrine ophthalmic solution in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving phenylephrine and ketorolac, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using phenylephrine and ketorolac with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Aceclofenac
• Acemetacin
• Amtolmetin Guacil
• Aspirin
• Bromfenac
• Bufexamac
• Celecoxib
• Choline Salicylate
• Clonixin
• Clorgyline
• Dexibuprofen
• Dexketoprofen
• Diclofenac
• Diflunisal
• Dipyrone
• Droxicam
• Etodolac
• Etofenamate
• Etoricoxib
• Felbinac
• Fenoprofen
• Fepradinol
• Feprazone
• Floctafenine
• Flufenamic Acid
• Flurbiprofen
• Ibuprofen
• Indomethaci...