Phesgo

Generic name:hyaluronidase, pertuzumab, and trastuzumab [ HYE-al-ure-ON-i-dase, per-TOOZ-ue-mab, and-tras-TOOZ-ue-mab ]
Drug class:HER2 inhibitors

Medically reviewed by Philip Thornton, DipPharm. Last updated on Aug 16, 2020.

What is Phesgo?

Phesgo contains a combination of hyaluronidase, pertuzumab, and trastuzumabis.

Phesgo is a cancer medicine that is used alone or with other medicines to treat early-stage breast cancer.

Phesgo is also used to treat HER2-positive breast cancer that is advanced or has spread to other parts of the body (metastatic).

Phesgo is used for breast cancer only if your tumor tests positive for a protein called human epidermal growth factor receptor 2 (HER2). HER2 protein can speed the growth of cancer cells.

Warnings

Phesgo can cause life-threatening heart or lung problems. Call your doctor at once if you have trouble breathing, swelling or rapid weight gain, fast or pounding heartbeats, or if you feel light-headed.

Do not use if you are pregnant. Use effective birth control during treatment and for at least 7 months after your last dose.

Before taking this medicine

You should not be treated with Phesgo if you are allergic to hyaluronidase, pertuzumab, or trastuzumab.

To make sure Phesgo is safe for you, tell your doctor if you have ever had:

• congestive heart failure;

• a heart attack or heart rhythm disorder;

• uncontrolled high blood pressure;

• a weak immune system caused by chemotherapy...