Physiolyte
Generic name: sodium chloride, sodium gluconate, sodium acetate, potassium chloride, and magnesium chloride
Dosage form: irrigation solution
Drug class:Sterile irrigating solutions
Medically reviewed by Drugs.com. Last updated on Oct 22, 2021.
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Balanced Electrolyte Solution for Irrigation.
For All General Irrigation, Washing, and Rinsing Purposes.
Not for Injection by Usual Parenteral Route.
Physiolyte Description
Physiolyte is a sterile, nonpyrogenic solution of electrolytes in water for injection intended only for sterile irrigation, washing, and rinsing purposes.
Each 100 mL contains:
Sodium Chloride USP 0.53 g; Sodium Gluconate USP 0.5 g
Sodium Acetate Trihydrate USP 0.37 g; Potassium Chloride
USP 0.037 g; Magnesium Chloride Hexahydrate USP 0.03 g
Water for Injection USP qs
Glacial Acetic Acid USP has been added to adjust the pH
pH: 6.8 (6.3–7.3)
Calculated Osmolarity: The solution is isotonic (295 mOsmol/liter)
Concentration of Electrolytes (mEq/liter): Sodium 140
Potassium 5; Magnesium 3; Chloride 98; Acetate (CH3COO−) 27
Gluconate (HOCH2(CHOH)4COO−) 23
It contains no bacteriostat, antimicrobial agent or added buffer (except for pH adjustment) and is intended only for use as a single-dose or short procedure irrigation. When smaller volumes are required the unused portion should be discarded.
Physiolyte may be classified as a sterile irrigant, wash, rinse and pharmaceutical vehicle.
The formulas of the active ingredients are:
| Ingredients | Molecular Formula | Molecular Weight |
|---|---|---|
| Sodium Chloride USP | NaCl | 58.44 |
| Sodium Acetate Trihydrate USP | CH3COONa•3H2O | 136.08 |
| Potassium Chloride USP | KCl | 74.55 |
| Magnesium Chloride Hexahydrate USP | MgCl2•6H2
MEDICAL DEPARTMENTS
Cardiology
Pediatrics
Diabetes Care
Pre-natal Care
Ultrasound Echocardiogram
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