Physiosol Irrigation
Generic name: balanced electrolyte solution
Dosage form: for irrigation
Drug class:Sterile irrigating solutions
Medically reviewed by Drugs.com. Last updated on Jan 1, 2022.
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Balanced Electrolyte Solution for Irrigation
For All General Irrigation, Washing and Rinsing Purposes
Not for Injection By Usual Parenteral Routes
Semi-rigid Irrigation Container
Rx only
Physiosol Irrigation Description
PhysioSol™ is a sterile, nonpyrogenic solution of electrolytes in water for injection intended only for sterile irrigation, washing and rinsing purposes.
Each 100 mL of PhysioSol™ Irrigation contains sodium chloride 526 mg, sodium acetate 222 mg, sodium gluconate 502 mg, potassium chloride 37 mg, magnesium chloride hexahydrate 30 mg. The pH is 6.0 (5.0 to 6.5) adjusted with hydrochloric acid. The solution is isotonic (294 mOsmol/liter, calc.) and has the following electrolyte content (mEq/liter): Na+ 140, K+ 5, Mg++ 3, Cl− 98, HCO3− 50 alternates (27 as acetate and 23 as gluconate).
It contains no bacteriostat, antimicrobial agent or added buffer (except for pH adjustment) and is intended only for use as single-dose or short procedure irrigation. When smaller volumes are required the unused portion should be discarded.
PhysioSol™ may be classified as a sterile irrigant, wash, rinse and pharmaceutical vehicle.
Magnesium Chloride, USP is chemically designated magnesium chloride hexahydrate (MgCl2 • 6H2O), colorless, odorless flakes or crystals very soluble in water.
Potassium Chloride, USP is chemically designated KCl, a white granular powder freely soluble in water.
Sodium Chloride, USP is chemically designated NaCl, a white crystalline powder freely soluble in water.
Sodium Acetate, USP is chemically designated sodium acetate (C2H3O2Na), colorless crystals or white crystalline powder or flakes very soluble in water. It has the following structural formula:
