Posaconazole (oral/injection)

Generic name: posaconazole (oral/injection) [ poe-sa-KONE-a-zole ]
Brand name: Noxafil
Dosage forms: intravenous solution (18 mg/mL); oral delayed release tablet (100 mg); oral suspension (40 mg/mL)
Drug class:Azole antifungals

Medically reviewed by Drugs.com on Jul 13, 2021. Written by Cerner Multum.

What is posaconazole?

Posaconazole is an antifungal medicine that is used to treat or prevent fungal infections that can spread throughout your body. posaconazole is sometimes used in people with weak immune systems caused by certain treatments such as chemotherapy or stem cell transplantation.

Posaconazole injection or delayed-release tablets are used to treat infections in adults and children at least 13 years old.

To prevent infections, posaconazole is given in the following ways:

• The injection is used in adults and children at least 2 years old.

• Delayed-release tablets are used in adults and children 2 years and older who weigh more than 88 pounds (40 kg).

• The oral suspension is used people at least 13 years old.

• The PowderMix is used in adults and children 2 years and older who weigh 88 pounds (40 kg) or less.

The oral suspension liquid form of posaconazole is also used to treat oral thrush (yeast infection of the mouth).

Posaconazole may also be used for purposes not listed in this medication guide.

Warnings

Tell your doctor about all your other medicines. Some drugs should not be used with posaconazole.

Before taking this medicine

You should not use posaconazole if you are allergic to posaconazole or similar antifungals such as fluconazole, itraconazole, ketoconazole, or voriconazole.

Some drugs should not be used with posaconazole. Your treatment plan may change if you also use:

• midazolam;

• pimozide;

• quinidine;

• sirolimus;

• cholesterol lowering medicines--atorvastatin, lovastatin, simvastatin, and others; or

• ergot medicine--dihydroergotamine, ergotamine, ergonovin...