Prevymis

Generic name:letermovir (oral/injection) [ le-TERM-oh-vir ]
Drug class:Miscellaneous antivirals

Medically reviewed by Philip Thornton, DipPharm. Last updated on May 2, 2021.

What is Prevymis?

Prevymis is an antiviral medicine used to help prevent cytomegalovirus (CMV) infection after a stem cell (bone marrow) transplant from a donor.

Prevymis is for use in adults who are seropositive for CMV. Seropositive means that the virus is in your blood even if you do not show any symptoms of infection.

A CMV-seropositive person is at risk for "reactivation" of the virus if the immune system becomes weak. While normally treatable, CMV infection can be serious in people undergoing a stem cell transplant.

Prevymis comes as a tablet or can be given by your doctor through an IV line (intravenously).

Warnings

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact with letermovir, and some drugs should not be used together.

Before taking this medicine

Some medicines can cause unwanted or dangerous effects when used with Prevymis. Your doctor may need to change your treatment plan if you use any of the following drugs:

• pimozide;

• cholesterol medication - pitavastatin, simvastatin; or

• ergot medicine - dihydroergotamine, ergotamine, ergonovine, methylergonovine.

To make sure Prevymis is safe for you, tell your doctor if you have ever had:

• kidney disease;