Prilocaine and epinephrine (Injection)

Medically reviewed by Drugs.com. Last updated on Jun 3, 2022.

Commonly used brand name(s)

In the U.S.

• Citanest Forte Dental

Available Dosage Forms:

• Solution

Therapeutic Class: Anesthetic, Amino Amide Combination

Pharmacologic Class: Epinephrine

Chemical Class: Prilocaine

Uses for prilocaine and epinephrine

Prilocaine and epinephrine combination injection is used to numb the mouth before a dental procedure.

Prilocaine and epinephrine is to be given by or under the direct supervision of your dentist.

Before using prilocaine and epinephrine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For prilocaine and epinephrine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to prilocaine and epinephrine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Because of prilocaine and epinephrine's toxicity, it should be used with extreme caution in children. Recommended doses should not be exceeded, and the patient should be carefully monitored during treatment.

Geriatric

No information is available on the relationship of age to the effects of prilocaine and epinephrine combination injection in geriatric patients. However, because of prilocaine and epinephrine's toxicity, it should be used with caution. Recommended doses should not be exceeded, and the patient should be carefully monitored during treatment.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving prilocaine and epinephrine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using prilocaine and epinephrine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Dihydroergotamine
• Isocarboxazid
• Linezolid
• Phenelzine
• Tranylcypromine

Using prilocaine and epinephrine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Amineptine
• Amitriptyline
• Amitriptylinoxide
• Amoxapine
• Benperidol
• Bromperidol
• Bucindolol
• Bupivacaine
• Bupivacaine Lipos...