Prilocaine Hydrochloride Injection
Dosage form: injection, solution
Drug class:Local injectable anesthetics
Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.
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For Local Anesthesia in Dentistry
Rx only
Prilocaine Hydrochloride Injection Description
Prilocaine Hydrochloride Injection, USP, 4% is a sterile, non pyrogenic isotonic solution that contains a local anesthetic agent and is administered parenterally by injection. See INDICATIONS AND USAGE for specific uses. The quantitative composition is shown in Table 1.
Prilocaine Hydrochloride Injection, USP, 4% contains prilocaine HCl, which is chemically designated as propanamide, N-(2-methyl-phenyl) -2- (propylamino)-, monohydrochloride and has the following structural formula:
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration.
The specific quantitative composition is shown in Table 1.
| Product Identification | Formula (mg/mL) | |
|---|---|---|
| Prilocaine HCl | pH | |
| Prilocaine Hydrochloride Injection, USP, 4% | 40.0 | 6.0 to 7.0 |
Note: Sodium hydroxide or hydrochloric acid may be used to adjust the pH of Prilocaine Hydrochloride Injection, USP, 4%.
Prilocaine Hydrochloride Injection - Clinical Pharmacology
Mechanism of Action
Prilocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, th...
