#
Propylthiouracil
  • Drugs A to Z

Propylthiouracil

Generic name: propylthiouracil [ PRO-pil-THYE-oh-URE-a-sil ]
Dosage form: oral tablet (50 mg)
Drug class:Antithyroid agents

Medically reviewed by Drugs.com on Jun 11, 2021. Written by Cerner Multum.

What is propylthiouracil?

Propylthiouracil is used to treat hyperthyroidism (overactive thyroid), Graves' disease, or toxic goiter (enlarged thyroid). propylthiouracil is sometimes given to control symptoms just before you undergo thyroid surgery or treatment with radioactive iodine.

Propylthiouracil may also be used for purposes not listed in this medication guide.

Warnings

Propylthiouracil can cause serious or fatal liver problems. Stop taking this medicine and call your doctor right away if you have upper stomach pain, nausea, vomiting, loss of appetite, fever, itching, tiredness, dark urine, clay-colored stools, or yellowing of your skin or eyes.

Before taking this medicine

You should not use propylthiouracil if you are allergic to it.

Tell your doctor if you have ever had liver problems.

In very rare cases, propylthiouracil has caused liver failure and death in pregnant women during the second or third trimester of pregnancy. Tell your doctor if you are pregnant or plan to become pregnant.

Tell your doctor if you are breastfeeding.

Propylthiouracil may cause liver failure in children, but is sometimes used in children who cannot be treated with other medications. Do not give propylthiouracil to a child without your doctor's advice.

...