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Protonix
  • Treatments
  • GERD

Protonix

Generic name:pantoprazole (oral/injection) [ pan-TOE-pra-zole ]
Drug class:Proton pump inhibitors

Medically reviewed by Kaci Durbin, MD. Last updated on Feb 3, 2021.

What is Protonix?

Protonix is a proton pump inhibitor that decreases the amount of acid produced in the stomach.

Protonix is used to treat erosive esophagitis (damage to the esophagus from stomach acid caused by gastroesophageal reflux disease, or GERD) in adults and children who are at least 5 years old. Pantoprazole is usually given for up to 8 weeks at a time while your esophagus heals.

Protonix is also used to treat Zollinger-Ellison syndrome and other conditions involving excess stomach acid.

Warnings

Protonix is not for the immediate relief of heartburn symptoms.

Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.

Long-term treatment with Protonix may also make it harder for your body to absorb vitamin B-12, resulting in a deficiency of this vitamin. Talk with your doctor if you need long-term Protonix treatment and you have concerns about vitamin B-12 deficiency.

Pantoprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.

Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.

Pantoprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or ar...