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Arestin
  • Professionals
  • FDA PI

Arestin

Generic name: minocycline hydrochloride
Dosage form: oral powder
Drug class:Tetracyclines

Medically reviewed by Drugs.com. Last updated on May 23, 2022.

Rx only

DESCRIPTION

Arestin (minocycline hydrochloride) microspheres, 1 mg is a subgingival sustained-release product containing the antibiotic minocycline hydrochloride incorporated into a bioresorbable polymer, Poly (glycolide-co-dl-lactide) or PGLA, for professional subgingival administration into periodontal pockets. Each unit-dose cartridge delivers minocycline hydrochloride equivalent to 1 mg of minocycline free base.

The molecular formula of minocycline hydrochloride is C23H27N3O7 ·HCl, and the molecular weight is 493.94. The structural formula of minocycline hydrochloride is:

Arestin - Clinical Pharmacology

Mechanism of Action

The mechanism of action of Arestin as an adjunct to scaling and root planing procedures for reduction of pocket depth in patients with adult periodontitis is unknown.