Argatroban

Generic name: argatroban [ ar-GAT-roe-ban ]
Brand name: Acova
Dosage form: intravenous solution (1 mg/mL; 100 mg/mL)
Drug class:Thrombin inhibitors

Medically reviewed by Drugs.com on Aug 20, 2021. Written by Cerner Multum.

What is argatroban?

Argatroban blocks the activity of certain clotting substances in the blood.

Argatroban is used to treat or prevent blood clots in adults who have thrombocytopenia (low levels of platelets in the blood) caused by using heparin. Argatroban is sometimes used in people who are undergoing a procedure called angioplasty (to open blocked arteries).

Argatroban may also be used for purposes not listed in this medication guide.

Warnings

You should not use argatroban if you have any major bleeding from a surgery, injury, or other cause.

Argatroban can make it easier for you to bleed, even from a minor injury. Seek medical attention if you have unusual bruising, or bleeding that will not stop.

Before taking this medicine

You should not use argatroban if you are allergic to it, or if you have any major bleeding from a surgery, injury, or other cause.

Tell your doctor if you have ever had:

• a stomach ulcer or bleeding;

• liver disease;

• a bleeding or blood clotting disorder (such as hemophilia);

• severe or uncontrolled high blood pressure;

• a spinal tap or epidural anesthesia; or

• major surgery (especially eye surgery, brain surgery, or spinal cord surgery).

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