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Ramucirumab
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Ramucirumab

Generic name: ramucirumab [ RA-mue-SIR-ue-mab ]
Brand name: Cyramza
Dosage form: intravenous solution (10 mg/mL)
Drug class:VEGF/VEGFR inhibitors

Medically reviewed by Drugs.com on Dec 1, 2021. Written by Cerner Multum.

What is ramucirumab?

Ramucirumab is used to treat stomach cancer, colorectal cancer, or non-small cell lung cancer that has spread to other parts of the body. Ramucirumab may be given alone or in combination with other cancer medicines.

Ramucirumab is usually given after other treatments have failed.

Ramucirumab may also be used for purposes not listed in this medication guide.

Warnings

Ramucirumab can increase your risk of serious bleeding. Stop using ramucirumab and call your doctor at once if you have severe stomach pain, bloody or tarry stools, coughing up blood, or any heavy or unusual bleeding.

Before taking this medicine

You should not use ramucirumab if you are allergic to it, or if you have:

Tell your doctor if you have ever had:

  • high blood pressure;

  • a thyroid disorder; or

  • an unhealed incision from recent surgery.

This medicine can harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine. Ramucirumab may affect fertility (your ability to have children).

Use birth control to prevent pregnancy while you are receiving ramucirumab, and for at least 3 months after your treatment ends.

You should not breastfeed while using this medicine.

How is ramucirumab given?

Ramucirumab is given as an infusion into a vein. A healthcare provider will give you this injection.

You may be given medication to prevent certain side effects while you are receiving ramucirumab.

Ramucirumab is sometimes given once every 2 weeks. Ramucirumab may also be given in a 21-day treatment cycle and you may only need to use the medicine during the first day of each cycle. Follow your doctor's dosing instructions very carefully.

While using ramucirumab, you may need frequent blood or urine tests. Your blood pressure will need to be checked often.

If you need surgery, tell the surgeon ahead of time that you are using ramucirumab.